Challenges in large-scale bioinformatics projects

Abstract Biological and biomedical research is increasingly conducted in large, interdisciplinary collaborations to address problems with significant societal impact, such as reducing antibiotic resistance, identifying disease sub-types, genes that control for drought tolerance plants. Many of these projects are data driven involve the collection analysis biological at a large-scale. As result, life-science projects, which frequently diverse, large geographically dispersed, have created unique challenges collaboration training. We examine communication multidisciplinary through an interview study 20 researchers. Our results show both inclusion multiple disciplines differences work culture influence life science. Using results, we discuss opportunities implications designing solutions better support collaborative tasks workflows scientists. In particular, science multi-institutional collaborations, groups rely on “mutual respect” collaboration. However, found nature cause technical language barriers methodology affect trust. use findings guide our recommendations technology also present training programs note necessity incorporating project management, language, discipline culture.